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What is a generic medication?
Wikipedia gives the following definition: Generic drug (pl. generic drugs, short: generics) is a drug which is produced and distributed without a brand name. A generic must contain the same active ingredients as the original formulation. In most cases, it is considered bioequivalent to the brand name counterpart with respect to pharmacokinetic and pharmacodynamic properties. By extension, therefore, generics are assumed to be identical in dose, strength, route of administration, safety, efficacy, and intended use.
Does a generic medication differ from a brand name drug?
Not much, actually. But there is a difference, of course. To see the difference more clearly we have made a table: click here
Why are generic pills cheaper than the brand name ones?
The principal reason for the reduced price of generic medicines is that the creation of the generic drug runs up less cost and therefore a lower price can be offered and still maintain profitability. Manufacturers of generic drugs are mainly able to avoid the following three costs that brand name pharmaceutical companies incur: (1) costs associated with the research and development of the drug; (2) costs associated obtaining regulatory approval (i.e. proving safety and efficacy of a drug); and (3) marketing costs. First, Generic manufacturers do not incur the cost of drug discovery and instead reverse-engineer existing brand name drugs to allow them to manufacture bioequivalent versions. Second, generic manufacturers do not bear the burden of proving the safety and efficacy of the drugs through clinical trials - rather, generic manufacturers must prove the generic drug’s bioequivalancy to the existing drug. Third, these companies receive the large benefit of the marketing and advertising that goes into pushing the innovator drug. The brand name drug has to prove itself in the eyes of the consumer, generic ones do not. The drugs that generic manufacturers are selling have been on the market for usually a decade or more and do not need additional advertising. For the same reason, generic manufacturers also do not give away sample doses to promote their products. The significant research, development and marketing costs incurred by the large pharmaceutical companies in introducing a new drug to the market is often cited as the reason for the high cost of new agents - they wish to recover these costs before the patent expires. Generic manufacturers do not incur these costs, with bioequivalence testing and manufacturing costing relatively little, and are able to charge significantly less than the brand.
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